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Evaluation of peptide designing strategy against subunit reassociation in mucin 1: A steered molecular dynamics approach

Subunit reassociation in mucin 1, a breast cancer tumor marker, is reported as one of the critical factors for its cytoplasmic activation. Inhibition of its heterodimeric association would therefore result in loss of its function and alter disease progression. The present study aimed at evaluating p...

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Detalles Bibliográficos
Autores principales: Lesitha Jeeva Kumari, J., Jesu Jaya Sudan, R., Sudandiradoss, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560680/
https://www.ncbi.nlm.nih.gov/pubmed/28817726
http://dx.doi.org/10.1371/journal.pone.0183041