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Ouabain affects cell migration via Na,K-ATPase-p130cas and via nucleus-centrosome association

Na,K-ATPase is a membrane protein that catalyzes ATP to maintain transmembrane sodium and potassium gradients. In addition, Na,K-ATPase also acts as a signal-transducing receptor for cardiotonic steroids such as ouabain and activates a number of signalling pathways. Several studies report that ouaba...

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Detalles Bibliográficos
Autores principales: Ou, Young, Pan, Chen Xuan, Zuo, Jeremy, van der Hoorn, Frans A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560699/
https://www.ncbi.nlm.nih.gov/pubmed/28817661
http://dx.doi.org/10.1371/journal.pone.0183343