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Ouabain affects cell migration via Na,K-ATPase-p130cas and via nucleus-centrosome association
Na,K-ATPase is a membrane protein that catalyzes ATP to maintain transmembrane sodium and potassium gradients. In addition, Na,K-ATPase also acts as a signal-transducing receptor for cardiotonic steroids such as ouabain and activates a number of signalling pathways. Several studies report that ouaba...
Autores principales: | Ou, Young, Pan, Chen Xuan, Zuo, Jeremy, van der Hoorn, Frans A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560699/ https://www.ncbi.nlm.nih.gov/pubmed/28817661 http://dx.doi.org/10.1371/journal.pone.0183343 |
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