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Pilot study of lithium to restore intestinal barrier function in severe graft-versus-host disease

Severe intestinal graft-vs-host disease (GVHD) after allogeneic hematopoietic cell transplantation (HCT) causes mucosal ulceration and induces innate and adaptive immune responses that amplify and perpetuate GVHD and the associated barrier dysfunction. Pharmacological agents to target mucosal barrie...

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Detalles Bibliográficos
Autores principales: Steinbach, Gideon, Hockenbery, David M., Huls, Gerwin, Furlong, Terry, Myerson, David, Loeb, Keith R., Fann, Jesse R., Castilla-Llorente, Christina, McDonald, George B., Martin, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560707/
https://www.ncbi.nlm.nih.gov/pubmed/28817727
http://dx.doi.org/10.1371/journal.pone.0183284