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Synthesis, radiosynthesis and in vitro evaluation of (18)F-Bodipy-C(16)/triglyceride as a dual modal imaging agent for brown adipose tissue

BACKGROUND: Brown adipose tissue research is in the focus in the field of endocrinology. We designed a dual-modal fluorescent/PET fatty acid based tracer on commercially available Bodipy-C(16), which can be synthesized to its corresponding triglyceride and which combines the benefits of fluorescent...

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Detalles Bibliográficos
Autores principales: Paulus, Andreas, Maenen, Marco, Drude, Natascha, Nascimento, Emmani B. M., van Marken Lichtenbelt, Wouter D., Mottaghy, Felix M., Bauwens, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560730/
https://www.ncbi.nlm.nih.gov/pubmed/28817670
http://dx.doi.org/10.1371/journal.pone.0182297