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Diflunisal inhibits prestin by chloride-dependent mechanism

The motor protein prestin is a member of the SLC26 family of anion antiporters and is essential to the electromotility of cochlear outer hair cells and for hearing. The only direct inhibitor of electromotility and the associated charge transfer is salicylate, possibly through direct interaction with...

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Detalles Bibliográficos
Autores principales: Duret, Guillaume, Pereira, Fred A., Raphael, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560734/
https://www.ncbi.nlm.nih.gov/pubmed/28817613
http://dx.doi.org/10.1371/journal.pone.0183046