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Diflunisal inhibits prestin by chloride-dependent mechanism
The motor protein prestin is a member of the SLC26 family of anion antiporters and is essential to the electromotility of cochlear outer hair cells and for hearing. The only direct inhibitor of electromotility and the associated charge transfer is salicylate, possibly through direct interaction with...
Autores principales: | Duret, Guillaume, Pereira, Fred A., Raphael, Robert M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560734/ https://www.ncbi.nlm.nih.gov/pubmed/28817613 http://dx.doi.org/10.1371/journal.pone.0183046 |
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