Cargando…

TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus

TPL-2 (COT, MAP3K8) kinase activates the MEK1/2-ERK1/2 MAPK signaling pathway in innate immune responses following TLR, TNFR1 and IL-1R stimulation. TPL-2 contributes to type-1/Th17-mediated autoimmunity and control of intracellular pathogens. We recently demonstrated TPL-2 reduces severe airway all...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kannan, Yashaswini, Entwistle, Lewis J., Pelly, Victoria S., Perez-Lloret, Jimena, Walker, Alan W., Ley, Steven C., Wilson, Mark S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560741/ https://www.ncbi.nlm.nih.gov/pubmed/28759611 http://dx.doi.org/10.1371/journal.ppat.1006536

Ejemplares similares

IL-4-producing ILC2s are required for the differentiation of T(H)2 cells following Heligmosomoides polygyrus infection
por: Pelly, VS, et al.
Publicado: (2016)

Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus
por: Reynolds, Lisa A., et al.
Publicado: (2012)

Experience-dependent olfactory behaviors of the parasitic nematode Heligmosomoides polygyrus
por: Ruiz, Felicitas, et al.
Publicado: (2017)

Superimposed visceral leishmanial infection aggravates response to Heligmosomoides polygyrus
por: González-Sánchez, M. E., et al.
Publicado: (2018)

Cultivation of Heligmosomoides Polygyrus: An Immunomodulatory Nematode Parasite and its Secreted Products
por: Johnston, Chris J. C., et al.
Publicado: (2015)

TPL-2 Regulates Macrophage Lipid Metabolism and M2 Differentiation to Control T(H)2-Mediated Immunopathology
por: Kannan, Yashaswini, et al.
Publicado: (2016)

Expansion and activation of CD4(+)CD25(+) regulatory T cells in Heligmosomoides polygyrus infection
por: Finney, Constance A M, et al.
Publicado: (2007)

C-type lectins from the nematode parasites Heligmosomoides polygyrus and Nippostrongylus brasiliensis
por: Harcus, Yvonne, et al.
Publicado: (2009)

Colitis Promotes Adaptation of an Intestinal Nematode: A Heligmosomoides Polygyrus Mouse Model System
por: Donskow-Łysoniewska, Katarzyna, et al.
Publicado: (2013)

In Vivo Nematicidal Potential of Camel Milk on Heligmosomoides Polygyrus Gastro-intestinal Nematode of Rodents
por: Alimi, D., et al.
Publicado: (2018)

Antihelminthic Activity of Lophira Lanceolata on Heligmosomoides polygyrus Using an Automated High-Throughput Method
por: Cédric, Yamssi, et al.
Publicado: (2023)

Redescription of Heligmosomoides neopolygyrus, Asakawa and Ohbayashi, 1986 (Nematoda: Heligmosomidae) from a Chinese Rodent, Apodemus peninsulae (Rodentia: Muridae); with comments on Heligmosomoides polygyrus polygyrus (Dujardin, 1845) and related species in China and Japan
por: Massoni, J., et al.
Publicado: (2012)

MyD88 Signaling Inhibits Protective Immunity to the Gastrointestinal Helminth Parasite Heligmosomoides polygyrus
por: Reynolds, Lisa A., et al.
Publicado: (2014)

TGF-β mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus
por: Smyth, Danielle J., et al.
Publicado: (2018)

The Helminth Parasite Heligmosomoides polygyrus Attenuates EAE in an IL-4Rα-Dependent Manner
por: White, Madeleine P. J., et al.
Publicado: (2020)

Cytokine elevation in the mouse small intestine at the early stage of infection with the gastrointestinal parasite Heligmosomoides polygyrus
por: NIIMI, Kanae, et al.
Publicado: (2021)

Benzimidazole and aminoalcohol derivatives show in vitro anthelmintic activity against Trichuris muris and Heligmosomoides polygyrus
por: Valderas-García, Elora, et al.
Publicado: (2022)

Trickle infection with Heligmosomoides polygyrus results in decreased worm burdens but increased intestinal inflammation and scarring
por: Ariyaratne, Anupama, et al.
Publicado: (2022)

IFNγ and IL-12 Restrict Th2 Responses during Helminth/Plasmodium Co-Infection and Promote IFNγ from Th2 Cells
por: Coomes, Stephanie M., et al.
Publicado: (2015)

Proteomic Analysis of Excretory-Secretory Products of Heligmosomoides polygyrus Assessed with Next-Generation Sequencing Transcriptomic Information
por: Moreno, Yovany, et al.
Publicado: (2011)

A protocol for generating germ-free Heligmosomoides polygyrus bakeri larvae for gnotobiotic helminth infection studies
por: Russell, Gabriel A., et al.
Publicado: (2021)

Heligmosomoides polygyrus Venom Allergen-like Protein-4 (HpVAL-4) is a sterol binding protein
por: Asojo, Oluwatoyin A., et al.
Publicado: (2018)

Tumor progression locus 2 reduces severe allergic airway inflammation by inhibiting Ccl24 production in dendritic cells
por: Kannan, Yashaswini, et al.
Publicado: (2017)

Novel O-linked methylated glycan antigens decorate secreted immunodominant glycoproteins from the intestinal nematode Heligmosomoides polygyrus
por: Hewitson, James P., et al.
Publicado: (2016)

Nematocidal Activity of Ethanol and Aqueous Extracts of Persea americana Seeds against Heligmosomoides polygyrus using the Worm Microtracker Method
por: Cédric, Yamssi, et al.
Publicado: (2023)

The Brown Alga Bifurcaria bifurcata Presents an Anthelmintic Activity on All Developmental Stages of the Parasitic Nematode Heligmosomoides polygyrus bakeri
por: Miclon, Morgane, et al.
Publicado: (2023)

Interleukin 4 promotes the development of ex-Foxp3 Th2 cells during immunity to intestinal helminths
por: Pelly, Victoria S., et al.
Publicado: (2017)

T-Bet Is Dependent on Stat-4 Inhibiting Acute Colitis but Not Stat-1 Using L4 Somatic Antigen of Heligmosomoides polygyrus
por: Endharti, Agustina Tri, et al.
Publicado: (2018)

The production of excretory-secretory molecules from Heligmosomoides polygyrus bakeri fourth stage larvae varies between mixed and single sex cultures
por: Maruszewska-Cheruiyot, Marta, et al.
Publicado: (2021)

Structural Requirements for Dihydrobenzoxazepinone Anthelmintics: Actions against Medically Important and Model Parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus, and Schistosoma mansoni
por: Partridge, Frederick A., et al.
Publicado: (2021)

Exposure of Heligmosomoides polygyrus and Trichuris muris to albendazole, albendazole sulfoxide, mebendazole and oxantel pamoate in vitro and in vivo to elucidate the pathway of drug entry into these gastrointestinal nematodes
por: Cowan, Noemi, et al.
Publicado: (2017)

Th2-dependent STAT6-regulated genes in intestinal epithelial cells mediate larval trapping during secondary Heligmosomoides polygyrus bakeri infection
por: Westermann, Stefanie, et al.
Publicado: (2023)

Epithelial-Cell-Derived Phospholipase A(2) Group 1B Is an Endogenous Anthelmintic
por: Entwistle, Lewis J., et al.
Publicado: (2017)

TPL‐2 kinase induces phagosome acidification to promote macrophage killing of bacteria
por: Breyer, Felix, et al.
Publicado: (2021)

Tamiz de problemas del lenguaje-TPL
por: Auza Benavides, Alejandra

TPL-2 negatively regulates interferon-β production in macrophages and myeloid dendritic cells
por: Kaiser, Frank, et al.
Publicado: (2009)

TPL2/COT/MAP3K8 (TPL2) Activation Promotes Androgen Depletion-Independent (ADI) Prostate Cancer Growth
por: Jeong, Joseph H., et al.
Publicado: (2011)

Tumor Progression Locus 2 (Tpl2) Kinase as a Novel Therapeutic Target for Cancer: Double-Sided Effects of Tpl2 on Cancer
por: Lee, Hye Won, et al.
Publicado: (2015)

The Gastrointestinal Helminth Heligmosomoides bakeri Suppresses Inflammation in a Model of Contact Hypersensitivity
por: Filbey, Kara J., et al.
Publicado: (2020)

Phylogenetics and genetic variation of Heligmosomoides thomomyos in Western pocket gophers (Thomomys spp.)
por: Hughes, Malorri R., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_egih3mi98s0f9qle7q6lu84l34