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Cross-reactivity, antivenomics, and neutralization of toxic activities of Lachesis venoms by polyspecific and monospecific antivenoms

BACKGROUND: Bothrops, Crotalus and Lachesis represent the most medically relevant genera of pitvipers in Central and South America. Similarity in venom phenotype and physiopathological profile of envenomings caused by the four nominal Lachesis species led us to hypothesize that an antivenom prepared...

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Detalles Bibliográficos
Autores principales: Madrigal, Marvin, Pla, Davinia, Sanz, Libia, Barboza, Elexandra, Arroyo-Portilla, Cynthia, Corrêa-Netto, Carlos, Gutiérrez, José María, Alape-Girón, Alberto, Flores-Díaz, Marietta, Calvete, Juan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560760/
https://www.ncbi.nlm.nih.gov/pubmed/28787445
http://dx.doi.org/10.1371/journal.pntd.0005793