Evolving Mistranslating tRNAs Through a Phenotypically Ambivalent Intermediate in Saccharomyces cerevisiae

The genetic code converts information from nucleic acid into protein. The genetic code was thought to be immutable, yet many examples in nature indicate that variations to the code provide a selective advantage. We used a sensitive selection system involving suppression of a deleterious allele (tti2...

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Detalles Bibliográficos
Autores principales: Berg, Matthew D., Hoffman, Kyle S., Genereaux, Julie, Mian, Safee, Trussler, Ryan S., Haniford, David B., O’Donoghue, Patrick, Brandl, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560794/
https://www.ncbi.nlm.nih.gov/pubmed/28576863
http://dx.doi.org/10.1534/genetics.117.203232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560794/
https://www.ncbi.nlm.nih.gov/pubmed/28576863
http://dx.doi.org/10.1534/genetics.117.203232

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