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Evolving Mistranslating tRNAs Through a Phenotypically Ambivalent Intermediate in Saccharomyces cerevisiae
The genetic code converts information from nucleic acid into protein. The genetic code was thought to be immutable, yet many examples in nature indicate that variations to the code provide a selective advantage. We used a sensitive selection system involving suppression of a deleterious allele (tti2...
Autores principales: | Berg, Matthew D., Hoffman, Kyle S., Genereaux, Julie, Mian, Safee, Trussler, Ryan S., Haniford, David B., O’Donoghue, Patrick, Brandl, Christopher J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560794/ https://www.ncbi.nlm.nih.gov/pubmed/28576863 http://dx.doi.org/10.1534/genetics.117.203232 |
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