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Complex Coding and Regulatory Polymorphisms in a Restriction Factor Determine the Susceptibility of Drosophila to Viral Infection

It is common to find that major-effect genes are an important cause of variation in susceptibility to infection. Here we have characterized natural variation in a gene called pastrel that explains over half of the genetic variance in susceptibility to the Drosophila C virus (DCV) in populations of D...

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Detalles Bibliográficos
Autores principales: Cao, Chuan, Cogni, Rodrigo, Barbier, Vincent, Jiggins, Francis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560813/
https://www.ncbi.nlm.nih.gov/pubmed/28630113
http://dx.doi.org/10.1534/genetics.117.201970