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AIRE is a critical spindle-associated protein in embryonic stem cells

Embryonic stem (ES) cells go though embryo-like cell cycles regulated by specialized molecular mechanisms. However, it is not known whether there are ES cell-specific mechanisms regulating mitotic fidelity. Here we showed that Autoimmune Regulator (Aire), a transcription coordinator involved in immu...

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Detalles Bibliográficos
Autores principales: Gu, Bin, Lambert, Jean-Philippe, Cockburn, Katie, Gingras, Anne-Claude, Rossant, Janet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560860/
https://www.ncbi.nlm.nih.gov/pubmed/28742026
http://dx.doi.org/10.7554/eLife.28131