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Tocilizumab Contributes to the Inflammatory Status of Mature Dendritic Cells through Interleukin-6 Receptor Subunits Modulation

Tocilizumab, a humanized anti-IL-6 receptor α (IL-6Rα) is widely used in the treatment of a panel of pathologies such as adult and juvenile rheumatoid arthritis (RA) and the systemic form of juvenile idiopathic arthritis in children. Its indications are expected to be largely extended to other infla...

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Detalles Bibliográficos
Autores principales: Meley, Daniel, Héraud, Audrey, Gouilleux-Gruart, Valerie, Ivanes, Fabrice, Velge-Roussel, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561017/
https://www.ncbi.nlm.nih.gov/pubmed/28861079
http://dx.doi.org/10.3389/fimmu.2017.00926