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Tocilizumab Contributes to the Inflammatory Status of Mature Dendritic Cells through Interleukin-6 Receptor Subunits Modulation
Tocilizumab, a humanized anti-IL-6 receptor α (IL-6Rα) is widely used in the treatment of a panel of pathologies such as adult and juvenile rheumatoid arthritis (RA) and the systemic form of juvenile idiopathic arthritis in children. Its indications are expected to be largely extended to other infla...
Autores principales: | Meley, Daniel, Héraud, Audrey, Gouilleux-Gruart, Valerie, Ivanes, Fabrice, Velge-Roussel, Florence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561017/ https://www.ncbi.nlm.nih.gov/pubmed/28861079 http://dx.doi.org/10.3389/fimmu.2017.00926 |
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