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Cytolytic DNA vaccine encoding lytic perforin augments the maturation of- and antigen presentation by- dendritic cells in a time-dependent manner

The use of cost-effective vaccines capable of inducing robust CD8(+) T cell immunity will contribute significantly towards the elimination of persistent viral infections and cancers worldwide. We have previously reported that a cytolytic DNA vaccine encoding an immunogen and a truncated mouse perfor...

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Detalles Bibliográficos
Autores principales: Wijesundara, Danushka K., Yu, Wenbo, Quah, Ben J. C., Eldi, Preethi, Hayball, John D., Diener, Kerrilyn R., Voskoboinik, Ilia, Gowans, Eric J., Grubor-Bauk, Branka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561019/
https://www.ncbi.nlm.nih.gov/pubmed/28819257
http://dx.doi.org/10.1038/s41598-017-08063-1