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Artificial DnaJ Protein for protein production and conformational diseases

For secreted proteins, proper protein folding is essential not only for biological function but also for secretion itself. Proteins with folding problems are trapped in the endoplasmic reticulum (ER) and are eventually degraded in the cytoplasm. In this study, we exploited co-expression of an artifi...

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Detalles Bibliográficos
Autores principales: Hishiya, Akinori, Koya, Keizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561034/
https://www.ncbi.nlm.nih.gov/pubmed/28819167
http://dx.doi.org/10.1038/s41598-017-09067-7