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Human cytomegalovirus escapes immune recognition by NK cells through the downregulation of B7-H6 by the viral genes US18 and US20

Human cytomegalovirus (HCMV) is a major human pathogen, causing serious diseases in immunocompromised populations and congenially infected neonates. One of the main immune cells acting against the virus are Natural Killer (NK) cells. Killing by NK cells is mediated by a small family of activating re...

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Detalles Bibliográficos
Autores principales: Charpak-Amikam, Yoav, Kubsch, Tobias, Seidel, Einat, Oiknine-Djian, Esther, Cavaletto, Noemi, Yamin, Rachel, Schmiedel, Dominik, Wolf, Dana, Gribaudo, Giorgio, Messerle, Martin, Cicin-Sain, Luka, Mandelboim, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561058/
https://www.ncbi.nlm.nih.gov/pubmed/28819195
http://dx.doi.org/10.1038/s41598-017-08866-2