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HDAC3 inhibition ameliorates spinal cord injury by immunomodulation

Following spinal cord injury (SCI), the innate immune response of microglia and infiltrating macrophages clears up cellular debris and promotes tissue repair, but it also inflicts secondary injury from inflammatory responses. Immunomodulation aimed at maximizing the beneficial effects while minimizi...

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Detalles Bibliográficos
Autores principales: Kuboyama, Tomoharu, Wahane, Shalaka, Huang, Yong, Zhou, Xiang, Wong, Jamie K., Koemeter-Cox, Andrew, Martini, Michael, Friedel, Roland H., Zou, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561061/
https://www.ncbi.nlm.nih.gov/pubmed/28819194
http://dx.doi.org/10.1038/s41598-017-08535-4