Cargando…

HDAC3 inhibition ameliorates spinal cord injury by immunomodulation

Following spinal cord injury (SCI), the innate immune response of microglia and infiltrating macrophages clears up cellular debris and promotes tissue repair, but it also inflicts secondary injury from inflammatory responses. Immunomodulation aimed at maximizing the beneficial effects while minimizi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kuboyama, Tomoharu, Wahane, Shalaka, Huang, Yong, Zhou, Xiang, Wong, Jamie K., Koemeter-Cox, Andrew, Martini, Michael, Friedel, Roland H., Zou, Hongyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561061/ https://www.ncbi.nlm.nih.gov/pubmed/28819194 http://dx.doi.org/10.1038/s41598-017-08535-4

Ejemplares similares

Author Correction: HDAC3 inhibition ameliorates spinal cord injury by immunomodulation
por: Kuboyama, Tomoharu, et al.
Publicado: (2018)

Diversified transcriptional responses of myeloid and glial cells in spinal cord injury shaped by HDAC3 activity
por: Wahane, Shalaka, et al.
Publicado: (2021)

Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2
por: Zhou, Xiang, et al.
Publicado: (2020)

Epigenetic Regulation Of Axon Regeneration and Glial Activation in Injury Responses
por: Wahane, Shalaka, et al.
Publicado: (2019)

Matrine promotes neural circuit remodeling to regulate motor function in a mouse model of chronic spinal cord injury
por: Tanabe, Norio, et al.
Publicado: (2019)

GRP78-Mediated Signaling Contributes to Axonal Growth Resulting in Motor Function Recovery in Spinal Cord-Injured Mice
por: Tanie, Yoshitaka, et al.
Publicado: (2020)

The Extract of Roots of Sophora flavescens Enhances the Recovery of Motor Function by Axonal Growth in Mice with a Spinal Cord Injury
por: Tanabe, Norio, et al.
Publicado: (2016)

Matrine Directly Activates Extracellular Heat Shock Protein 90, Resulting in Axonal Growth and Functional Recovery in Spinal Cord Injured-Mice
por: Tanabe, Norio, et al.
Publicado: (2018)

New reliable scoring system, Toyama mouse score, to evaluate locomotor function following spinal cord injury in mice
por: Shigyo, Michiko, et al.
Publicado: (2014)

Immunomodulation as a neuroprotective strategy after spinal cord injury
por: Monteiro, Susana, et al.
Publicado: (2018)

RNA Profiling of Mouse Ependymal Cells after Spinal Cord Injury Identifies the Oncostatin Pathway as a Potential Key Regulator of Spinal Cord Stem Cell Fate
por: Chevreau, Robert, et al.
Publicado: (2021)

Loss-of-function manipulations to identify roles of diverse glia and stromal cells during CNS scar formation
por: Wahane, Shalaka, et al.
Publicado: (2021)

Correction to: Loss‑of‑function manipulations to identify roles of diverse glia and stromal cells during CNS scar formation
por: Wahane, Shalaka, et al.
Publicado: (2022)

The immunomodulator decoy receptor 3 improves locomotor functional recovery after spinal cord injury
por: Chiu, Chuan-Wen, et al.
Publicado: (2016)

L-Arginine Depletion Improves Spinal Cord Injury via Immunomodulation and Nitric Oxide Reduction
por: Erens, Céline, et al.
Publicado: (2022)

Attenuation of Cerebral Ischemic Injury in Smad1 Deficient Mice
por: Wong, Jamie K., et al.
Publicado: (2015)

CO-Releasing Molecule (CORM)-3 Ameliorates Spinal Cord-Blood Barrier Disruption Following Injury to the Spinal Cord
por: Zheng, Gang, et al.
Publicado: (2020)

Exercise Ameliorates Spinal Cord Injury by Changing DNA Methylation
por: Davaa, Ganchimeg, et al.
Publicado: (2021)

Melatonin Synergizes With Methylprednisolone to Ameliorate Acute Spinal Cord Injury
por: Bi, Jiaqi, et al.
Publicado: (2022)

Curcumin Ameliorates Ischemia-Induced Limb Injury Through Immunomodulation
por: Liu, Yang, et al.
Publicado: (2016)

Congenital exercise ability ameliorates muscle atrophy but not spinal cord recovery in spinal cord injury mouse model
por: Tai, Po-An, et al.
Publicado: (2019)

The Anti-Inflammatory Compound Curcumin Enhances Locomotor and Sensory Recovery after Spinal Cord Injury in Rats by Immunomodulation
por: Machova Urdzikova, Lucia, et al.
Publicado: (2015)

A Call to Action: Promoting Diversity, Equity, and Inclusion in Parkinson’s Research and Care
por: Siddiqi, Bernadette, et al.
Publicado: (2021)

Sepsis-associated neuroinflammation in the spinal cord
por: Hirotsu, Akiko, et al.
Publicado: (2022)

Immunomodulation with Human Umbilical Cord Blood Stem Cells Ameliorates Ischemic Brain Injury – A Brain Transcriptome Profiling Analysis
por: Shiao, Maple L., et al.
Publicado: (2019)

Amelioration of spinal cord injury in rats by blocking peroxynitrite/calpain activity
por: Khan, Mushfiquddin, et al.
Publicado: (2018)

Neuroprotection and immunomodulation by xenografted human mesenchymal stem cells following spinal cord ventral root avulsion
por: Ribeiro, Thiago B., et al.
Publicado: (2015)

Resveratrol ameliorates autophagic flux to promote functional recovery in rats after spinal cord injury
por: Wang, Peng, et al.
Publicado: (2018)

Amelioration of Autoimmune Diabetes of NOD Mice by Immunomodulating Probiotics
por: Kim, Tae Kang, et al.
Publicado: (2020)

Necrosulfonamide Ameliorates Neurological Impairment in Spinal Cord Injury by Improving Antioxidative Capacity
por: Jiao, Jianhang, et al.
Publicado: (2020)

Erythropoietin inhibits ferroptosis and ameliorates neurological function after spinal cord injury
por: Kang, Yu, et al.
Publicado: (2022)

Class I histone deacetylase (HDAC) inhibitor CI-994 promotes functional recovery following spinal cord injury
por: Zhang, Suxiang, et al.
Publicado: (2018)

HDAC3 Inhibition Promotes Alternative Activation of Macrophages but Does Not Affect Functional Recovery after Spinal Cord Injury
por: Sanchez, Selien, et al.
Publicado: (2018)

Distinct Vulnerability and Resilience of Human Neuroprogenitor Subtypes in Cerebral Organoid Model of Prenatal Hypoxic Injury
por: Daviaud, Nicolas, et al.
Publicado: (2019)

Relationship between Spinal Cord Volume and Spinal Cord Injury due to Spinal Shortening
por: Qiu, Feng, et al.
Publicado: (2015)

Multifunctional biomimetic spinal cord: New approach to repair spinal cord injuries
por: Liu, Yang, et al.
Publicado: (2017)

A Systematic Strategy for Discovering a Therapeutic Drug for Alzheimer’s Disease and Its Target Molecule
por: Yang, Zhiyou, et al.
Publicado: (2017)

Natural Medicines and Their Underlying Mechanisms of Prevention and Recovery from Amyloid Β-Induced Axonal Degeneration in Alzheimer’s Disease
por: Kuboyama, Tomoharu, et al.
Publicado: (2020)

Incidence of spinal cord injuries in Germany
por: Rau, Yannick, et al.
Publicado: (2022)

Atractylenolide III ameliorates spinal cord injury in rats by modulating microglial/macrophage polarization
por: Xue, Meng‐Tong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_7dsdsqlr66trnrn6ttgksh530q