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Automated Segmentation of Light-Sheet Fluorescent Imaging to Characterize Experimental Doxorubicin-Induced Cardiac Injury and Repair

This study sought to develop an automated segmentation approach based on histogram analysis of raw axial images acquired by light-sheet fluorescent imaging (LSFI) to establish rapid reconstruction of the 3-D zebrafish cardiac architecture in response to doxorubicin-induced injury and repair. Input i...

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Detalles Bibliográficos
Autores principales: Packard, René R. Sevag, Baek, Kyung In, Beebe, Tyler, Jen, Nelson, Ding, Yichen, Shi, Feng, Fei, Peng, Kang, Bong Jin, Chen, Po-Heng, Gau, Jonathan, Chen, Michael, Tang, Jonathan Y., Shih, Yu-Huan, Ding, Yonghe, Li, Debiao, Xu, Xiaolei, Hsiai, Tzung K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561066/
https://www.ncbi.nlm.nih.gov/pubmed/28819303
http://dx.doi.org/10.1038/s41598-017-09152-x