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Automated Segmentation of Light-Sheet Fluorescent Imaging to Characterize Experimental Doxorubicin-Induced Cardiac Injury and Repair
This study sought to develop an automated segmentation approach based on histogram analysis of raw axial images acquired by light-sheet fluorescent imaging (LSFI) to establish rapid reconstruction of the 3-D zebrafish cardiac architecture in response to doxorubicin-induced injury and repair. Input i...
Autores principales: | Packard, René R. Sevag, Baek, Kyung In, Beebe, Tyler, Jen, Nelson, Ding, Yichen, Shi, Feng, Fei, Peng, Kang, Bong Jin, Chen, Po-Heng, Gau, Jonathan, Chen, Michael, Tang, Jonathan Y., Shih, Yu-Huan, Ding, Yonghe, Li, Debiao, Xu, Xiaolei, Hsiai, Tzung K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561066/ https://www.ncbi.nlm.nih.gov/pubmed/28819303 http://dx.doi.org/10.1038/s41598-017-09152-x |
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