Silencing of TGF-β1 in tumor cells impacts MMP-9 in tumor microenvironment

Transforming growth factor (TGF)-β1 contributes to autocrine and paracrine functions in the tumor microenvironment (TME). The present study examined the effects of TGF-β1 crosstalk in TME and its role in mediating tumor formation and progression by targeted abrogation of TGF-β1 expression in metasta...

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Detalles Bibliográficos
Autores principales: Moore-Smith, Lakisha D., Isayeva, Tatyana, Lee, Joo Hyoung, Frost, Andra, Ponnazhagan, Selvarangan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561077/
https://www.ncbi.nlm.nih.gov/pubmed/28819116
http://dx.doi.org/10.1038/s41598-017-09062-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561077/
https://www.ncbi.nlm.nih.gov/pubmed/28819116
http://dx.doi.org/10.1038/s41598-017-09062-y

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