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Silencing of TGF-β1 in tumor cells impacts MMP-9 in tumor microenvironment
Transforming growth factor (TGF)-β1 contributes to autocrine and paracrine functions in the tumor microenvironment (TME). The present study examined the effects of TGF-β1 crosstalk in TME and its role in mediating tumor formation and progression by targeted abrogation of TGF-β1 expression in metasta...
Autores principales: | Moore-Smith, Lakisha D., Isayeva, Tatyana, Lee, Joo Hyoung, Frost, Andra, Ponnazhagan, Selvarangan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561077/ https://www.ncbi.nlm.nih.gov/pubmed/28819116 http://dx.doi.org/10.1038/s41598-017-09062-y |
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