Distinct carbon sources affect structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells

The immature phenotype of human pluripotent stem cell derived cardiomyocytes (hPSC-CMs) constrains their potential in cell therapy and drug testing. In this study, we report that shifting hPSC-CMs from glucose-containing to galactose- and fatty acid-containing medium promotes their fast maturation i...

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Detalles Bibliográficos
Autores principales: Correia, Cláudia, Koshkin, Alexey, Duarte, Patrícia, Hu, Dongjian, Teixeira, Ana, Domian, Ibrahim, Serra, Margarida, Alves, Paula M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561128/
https://www.ncbi.nlm.nih.gov/pubmed/28819274
http://dx.doi.org/10.1038/s41598-017-08713-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561128/
https://www.ncbi.nlm.nih.gov/pubmed/28819274
http://dx.doi.org/10.1038/s41598-017-08713-4

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