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Delta inulin-based adjuvants promote the generation of polyfunctional CD4(+) T cell responses and protection against Mycobacterium tuberculosis infection

There is an urgent need for the rational design of safe and effective vaccines to protect against chronic bacterial pathogens such as Mycobacterium tuberculosis. Advax™ is a novel adjuvant based on delta inulin microparticles that enhances immunity with a minimal inflammatory profile and has entered...

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Detalles Bibliográficos
Autores principales: Counoupas, Claudio, Pinto, Rachel, Nagalingam, Gayathri, Britton, Warwick J., Petrovsky, Nikolai, Triccas, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561132/
https://www.ncbi.nlm.nih.gov/pubmed/28819247
http://dx.doi.org/10.1038/s41598-017-09119-y