The Conserved Sonic Hedgehog Limb Enhancer Consists of Discrete Functional Elements that Regulate Precise Spatial Expression

Expression of sonic hedgehog (Shh) in the limb bud is regulated by an enhancer called the zone of polarizing activity regulatory sequence (ZRS), which, in evolution, belongs to an ancient group of highly conserved cis regulators found in all classes of vertebrates. Here, we examined the endogenous Z...

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Detalles Bibliográficos
Autores principales: Lettice, Laura A., Devenney, Paul, De Angelis, Carlo, Hill, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561167/
https://www.ncbi.nlm.nih.gov/pubmed/28793263
http://dx.doi.org/10.1016/j.celrep.2017.07.037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561167/
https://www.ncbi.nlm.nih.gov/pubmed/28793263
http://dx.doi.org/10.1016/j.celrep.2017.07.037

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