Generation and intracellular trafficking of a polysialic acid-carrying fragment of the neural cell adhesion molecule NCAM to the cell nucleus

Polysialic acid (PSA) and its major protein carrier, the neural cell adhesion molecule NCAM, play important roles in many nervous system functions during development and in adulthood. Here, we show that a PSA-carrying NCAM fragment is generated at the plasma membrane by matrix metalloproteases and t...

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Detalles Bibliográficos
Autores principales: Westphal, Nina, Loers, Gabriele, Lutz, David, Theis, Thomas, Kleene, Ralf, Schachner, Melitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561184/
https://www.ncbi.nlm.nih.gov/pubmed/28819302
http://dx.doi.org/10.1038/s41598-017-09468-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561184/
https://www.ncbi.nlm.nih.gov/pubmed/28819302
http://dx.doi.org/10.1038/s41598-017-09468-8

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