A novel in vitro potency assay of antisera against Thai Naja kaouthia based on nicotinic acetylcholine receptor binding

Snake envenomation is an important medical problem. One of the hurdles in antivenom development is the in vivo assay of antivenom potency which is expensive, gives variable results and kills many animals. We report a novel in vitro assay involving the specific binding of the postsynaptic neurotoxins...

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Detalles Bibliográficos
Autores principales: Ratanabanangkoon, Kavi, Simsiriwong, Pavinee, Pruksaphon, Kritsada, Tan, Kae Yi, Eursakun, Sukanya, Tan, Choo Hock, Chantrathonkul, Bunkuea, Wongwadhunyoo, Wongsakorn, Youngchim, Sirida, Tan, Nget Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561211/
https://www.ncbi.nlm.nih.gov/pubmed/28819275
http://dx.doi.org/10.1038/s41598-017-08962-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561211/
https://www.ncbi.nlm.nih.gov/pubmed/28819275
http://dx.doi.org/10.1038/s41598-017-08962-3

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