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A novel in vitro potency assay of antisera against Thai Naja kaouthia based on nicotinic acetylcholine receptor binding
Snake envenomation is an important medical problem. One of the hurdles in antivenom development is the in vivo assay of antivenom potency which is expensive, gives variable results and kills many animals. We report a novel in vitro assay involving the specific binding of the postsynaptic neurotoxins...
Autores principales: | Ratanabanangkoon, Kavi, Simsiriwong, Pavinee, Pruksaphon, Kritsada, Tan, Kae Yi, Eursakun, Sukanya, Tan, Choo Hock, Chantrathonkul, Bunkuea, Wongwadhunyoo, Wongsakorn, Youngchim, Sirida, Tan, Nget Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561211/ https://www.ncbi.nlm.nih.gov/pubmed/28819275 http://dx.doi.org/10.1038/s41598-017-08962-3 |
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