Linker histone H1 prevents R-loop accumulation and genome instability in heterochromatin

Linker histone H1 is an important structural component of chromatin that stabilizes the nucleosome and compacts the nucleofilament into higher-order structures. The biology of histone H1 remains, however, poorly understood. Here we show that Drosophila histone H1 (dH1) prevents genome instability as...

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Detalles Bibliográficos
Autores principales: Bayona-Feliu, Aleix, Casas-Lamesa, Anna, Reina, Oscar, Bernués, Jordi, Azorín, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561251/
https://www.ncbi.nlm.nih.gov/pubmed/28819201
http://dx.doi.org/10.1038/s41467-017-00338-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561251/
https://www.ncbi.nlm.nih.gov/pubmed/28819201
http://dx.doi.org/10.1038/s41467-017-00338-5

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