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Deletion of EP4 in S100a4-lineage cells reduces scar tissue formation during early but not later stages of tendon healing
Tendon injuries heal via scar tissue rather than regeneration. This healing response forms adhesions between the flexor tendons in the hand and surrounding tissues, resulting in impaired range of motion and hand function. Mechanistically, inflammation has been strongly linked to adhesion formation,...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561254/ https://www.ncbi.nlm.nih.gov/pubmed/28819185 http://dx.doi.org/10.1038/s41598-017-09407-7 |