miR-16 and miR-125b are involved in barrier function dysregulation through the modulation of claudin-2 and cingulin expression in the jejunum in IBS with diarrhoea

OBJECTIVE: Micro-RNAs (miRNAs) play a crucial role in controlling intestinal epithelial barrier function partly by modulating the expression of tight junction (TJ) proteins. We have previously shown differential messenger RNA (mRNA) expression correlated with ultrastructural abnormalities of the epi...

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Detalles Bibliográficos
Autores principales: Martínez, Cristina, Rodiño-Janeiro, Bruno K, Lobo, Beatriz, Stanifer, Megan L, Klaus, Bernd, Granzow, Martin, González-Castro, Ana M, Salvo-Romero, Eloisa, Alonso-Cotoner, Carmen, Pigrau, Marc, Roeth, Ralph, Rappold, Gudrun, Huber, Wolfgang, González-Silos, Rosa, Lorenzo, Justo, de Torres, Inés, Azpiroz, Fernando, Boulant, Steeve, Vicario, María, Niesler, Beate, Santos, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Neurogastroenterology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561373/
https://www.ncbi.nlm.nih.gov/pubmed/28082316
http://dx.doi.org/10.1136/gutjnl-2016-311477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561373/
https://www.ncbi.nlm.nih.gov/pubmed/28082316
http://dx.doi.org/10.1136/gutjnl-2016-311477

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