Population Pharmacokinetic Analysis of Bortezomib in Pediatric Leukemia Patients: Model‐Based Support for Body Surface Area‐Based Dosing Over the 2‐ to 16‐Year Age Range

This population analysis described the pharmacokinetics of bortezomib after twice‐weekly, repeat‐dose, intravenous administration in pediatric patients participating in 2 clinical trials: the phase 2 AALL07P1 (NCT00873093) trial in relapsed acute lymphoblastic leukemia and the phase 3 AAML1031 (NCT0...

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Detalles Bibliográficos
Autores principales: Hanley, Michael J., Mould, Diane R., Taylor, Timothy J., Gupta, Neeraj, Suryanarayan, Kaveri, Neuwirth, Rachel, Esseltine, Dixie‐Lee, Horton, Terzah M., Aplenc, Richard, Alonzo, Todd A., Lu, Xiaomin, Milton, Ashley, Venkatakrishnan, Karthik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Pediatric Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561493/
https://www.ncbi.nlm.nih.gov/pubmed/28419486
http://dx.doi.org/10.1002/jcph.906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561493/
https://www.ncbi.nlm.nih.gov/pubmed/28419486
http://dx.doi.org/10.1002/jcph.906

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