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Highly active antiretroviral therapy dysregulates proliferation and differentiation of human pre-adipocytes

AIM: To investigate the mechanism(s) by which potential effects of multi-drug highly-active antiretroviral therapy contributes to lipodystrophy syndrome. METHODS: Preadipocytes from healthy donors were assessed for proliferation and differentiation in the presence of nucleoside reverse transcriptase...

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Detalles Bibliográficos
Autores principales: Jones, Eyone, Mazirka, Pavel, McNurlan, Margaret A, Darras, Frank, Gelato, Marie C, Caso, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561499/
https://www.ncbi.nlm.nih.gov/pubmed/28868243
http://dx.doi.org/10.5501/wjv.v6.i3.53