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Peptide-Appended Permethylated β-Cyclodextrins with Hydrophilic and Hydrophobic Spacers

[Image: see text] A novel synthetic methodology, employing a combination of the strain-promoted azide–alkyne cycloaddition and maleimide–thiol reactions, for the preparation of permethylated β-cyclodextrin-linker-peptidyl conjugates is reported. Two different bifunctional maleimide cross-linking pro...

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Detalles Bibliográficos
Autores principales: Al Temimi, Abbas H. K., Boltje, Thomas J., Zollinger, Daniel, Rutjes, Floris P. J. T., Feiters, Martin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561536/
https://www.ncbi.nlm.nih.gov/pubmed/28697600
http://dx.doi.org/10.1021/acs.bioconjchem.7b00319