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SRSF1 promotes vascular smooth muscle cell proliferation through a Δ133p53/EGR1/KLF5 pathway

Though vascular smooth muscle cell (VSMC) proliferation underlies all cardiovascular hyperplastic disorders, our understanding of the molecular mechanisms responsible for this cellular process is still incomplete. Here we report that SRSF1 (serine/arginine-rich splicing factor 1), an essential splic...

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Detalles Bibliográficos
Autores principales: Xie, Ning, Chen, Min, Dai, Rilei, Zhang, Yan, Zhao, Hanqing, Song, Zhiming, Zhang, Lufeng, Li, Zhenyan, Feng, Yuanqing, Gao, Hua, Wang, Li, Zhang, Ting, Xiao, Rui-Ping, Wu, Jianxin, Cao, Chun-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561544/
https://www.ncbi.nlm.nih.gov/pubmed/28799539
http://dx.doi.org/10.1038/ncomms16016