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The impact of RNA sequence library construction protocols on transcriptomic profiling of leukemia

BACKGROUND: RNA sequencing (RNA-seq) has become an indispensable tool to identify disease associated transcriptional profiles and determine the molecular underpinnings of diseases. However, the broad adaptation of the methodology into the clinic is still hampered by inconsistent results from differe...

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Detalles Bibliográficos
Autores principales: Kumar, Ashwini, Kankainen, Matti, Parsons, Alun, Kallioniemi, Olli, Mattila, Pirkko, Heckman, Caroline A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561555/
https://www.ncbi.nlm.nih.gov/pubmed/28818039
http://dx.doi.org/10.1186/s12864-017-4039-1