Non-canonical soluble amyloid-beta aggregates and plaque buffering: controversies and future directions for target discovery in Alzheimer’s disease

The specific amyloid-beta (Aβ) species or other amyloid-precursor protein cleavage products that are most directly related to human neurodegeneration and clinical dementia of the Alzheimer’s type have not yet been directly identified. Without a clear understanding of the most relevant species, it is...

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Detalles Bibliográficos
Autores principales: Brody, David L., Jiang, Hao, Wildburger, Norelle, Esparza, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561579/
https://www.ncbi.nlm.nih.gov/pubmed/28818091
http://dx.doi.org/10.1186/s13195-017-0293-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561579/
https://www.ncbi.nlm.nih.gov/pubmed/28818091
http://dx.doi.org/10.1186/s13195-017-0293-3

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