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Non-canonical soluble amyloid-beta aggregates and plaque buffering: controversies and future directions for target discovery in Alzheimer’s disease

The specific amyloid-beta (Aβ) species or other amyloid-precursor protein cleavage products that are most directly related to human neurodegeneration and clinical dementia of the Alzheimer’s type have not yet been directly identified. Without a clear understanding of the most relevant species, it is...

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Detalles Bibliográficos
Autores principales:	Brody, David L., Jiang, Hao, Wildburger, Norelle, Esparza, Thomas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561579/ https://www.ncbi.nlm.nih.gov/pubmed/28818091 http://dx.doi.org/10.1186/s13195-017-0293-3

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