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A new method for sequencing the hypervariable Plasmodium falciparum gene var2csa from clinical samples

BACKGROUND: VAR2CSA, a member of the Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family, mediates the binding of P. falciparum-infected erythrocytes to chondroitin sulfate A, a surface-associated molecule expressed in placental cells, and plays a central role in the pathogenesis of...

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Detalles Bibliográficos
Autores principales: Dara, Antoine, Travassos, Mark A., Adams, Matthew, Schaffer DeRoo, Sarah, Drábek, Elliott F., Agrawal, Sonia, Laufer, Miriam K., Plowe, Christopher V., Silva, Joana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561619/
https://www.ncbi.nlm.nih.gov/pubmed/28818101
http://dx.doi.org/10.1186/s12936-017-1976-8