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Distinct white matter microstructural abnormalities and extracellular water increases relate to cognitive impairment in Alzheimer’s disease with and without cerebrovascular disease

BACKGROUND: Mixed vascular and neurodegenerative dementia, such as Alzheimer’s disease (AD) with concomitant cerebrovascular disease, has emerged as the leading cause of age-related cognitive impairment. The brain white matter (WM) microstructural changes in neurodegeneration well-documented by diff...

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Detalles Bibliográficos
Autores principales: Ji, Fang, Pasternak, Ofer, Liu, Siwei, Loke, Yng Miin, Choo, Boon Linn, Hilal, Saima, Xu, Xin, Ikram, Mohammad Kamran, Venketasubramanian, Narayanaswamy, Chen, Christopher Li-Hsian, Zhou, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561637/
https://www.ncbi.nlm.nih.gov/pubmed/28818116
http://dx.doi.org/10.1186/s13195-017-0292-4