Osteopontin deficiency protects mice from cholesterol gallstone formation by reducing expression of intestinal NPC1L1

Homeostasis of cholesterol is regulated by absorption in the intestine and synthesis in the liver. The authors previously demonstrated that OPN (osteopontin) exhibits the ability to alter hepatic cholesterol metabolism, thus affecting cholesterol gallstone formation in mice. The present study invest...

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Detalles Bibliográficos
Autores principales: Lin, Jing, Shao, Wei-Qing, Chen, Qing-Zhi, Zhu, Wen-Wei, Lu, Lu, Jia, Hu-Liang, Chen, Jin-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561929/
https://www.ncbi.nlm.nih.gov/pubmed/28627641
http://dx.doi.org/10.3892/mmr.2017.6774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561929/
https://www.ncbi.nlm.nih.gov/pubmed/28627641
http://dx.doi.org/10.3892/mmr.2017.6774

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