Effects of metal ions on the structure and activity of a human anti-cyclin D1 single-chain variable fragment AD5

Cyclin D1 has become a potential target for anti-tumor therapy. Recently, a novel human anti-cyclin D1 single-chain variable fragment (AD5) was identified, which demonstrated specific binding activity to cyclin D1 and exhibited anti-tumor effects. However, the detailed characteristics of AD5 remain...

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Detalles Bibliográficos
Autores principales: Yang, Ning, Yao, Nannan, Liao, Xiangzhi, Xie, Xiaona, Wu, Yan, Fan, Chuanxi, Zhao, Jialiang, Li, Guiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561975/
https://www.ncbi.nlm.nih.gov/pubmed/28627625
http://dx.doi.org/10.3892/mmr.2017.6756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561975/
https://www.ncbi.nlm.nih.gov/pubmed/28627625
http://dx.doi.org/10.3892/mmr.2017.6756

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