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Effects of metal ions on the structure and activity of a human anti-cyclin D1 single-chain variable fragment AD5
Cyclin D1 has become a potential target for anti-tumor therapy. Recently, a novel human anti-cyclin D1 single-chain variable fragment (AD5) was identified, which demonstrated specific binding activity to cyclin D1 and exhibited anti-tumor effects. However, the detailed characteristics of AD5 remain...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561975/ https://www.ncbi.nlm.nih.gov/pubmed/28627625 http://dx.doi.org/10.3892/mmr.2017.6756 |