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Rapamycin inhibits CaCl(2)-induced thoracic aortic aneurysm formation in rats through mTOR-mediated suppression of proinflammatory mediators
The aim of the present study was to investigate the effect of the mammalian target of rapamycin (mTOR) signaling pathway on thoracic aortic aneurysm (TAA) development. The study used a calcium chloride (CaCl(2))-induced rat TAA model to explore the potential role of mTOR signaling pathway in the dis...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561979/ https://www.ncbi.nlm.nih.gov/pubmed/28656223 http://dx.doi.org/10.3892/mmr.2017.6844 |