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Rapamycin inhibits CaCl(2)-induced thoracic aortic aneurysm formation in rats through mTOR-mediated suppression of proinflammatory mediators

The aim of the present study was to investigate the effect of the mammalian target of rapamycin (mTOR) signaling pathway on thoracic aortic aneurysm (TAA) development. The study used a calcium chloride (CaCl(2))-induced rat TAA model to explore the potential role of mTOR signaling pathway in the dis...

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Detalles Bibliográficos
Autores principales: Cao, Jiumei, Wu, Qihong, Geng, Liang, Chen, Xiaonan, Shen, Weifeng, Wu, Fang, Chen, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561979/
https://www.ncbi.nlm.nih.gov/pubmed/28656223
http://dx.doi.org/10.3892/mmr.2017.6844