miR-203 inhibits the expression of collagen-related genes and the proliferation of hepatic stellate cells through a SMAD3-dependent mechanism

Activation of hepatic stellate cells (HSCs) is a pivotal event during hepatic fibrogenesis. Activated HSCs are the main source of collagen and other extracellular matrix (ECM) components, and emerging antifibrotic therapies are aimed at preventing ECM synthesis and deposition. MicroRNAs (miRNAs) hav...

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Detalles Bibliográficos
Autores principales: Hu, Danping, Hu, Yibing, Xu, Wangwang, Yu, Huanhuan, Yang, Naibin, Ni, Shunlan, Fu, Rongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561992/
https://www.ncbi.nlm.nih.gov/pubmed/28586069
http://dx.doi.org/10.3892/mmr.2017.6702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561992/
https://www.ncbi.nlm.nih.gov/pubmed/28586069
http://dx.doi.org/10.3892/mmr.2017.6702

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