Cargando…

miR-203 inhibits the expression of collagen-related genes and the proliferation of hepatic stellate cells through a SMAD3-dependent mechanism

Activation of hepatic stellate cells (HSCs) is a pivotal event during hepatic fibrogenesis. Activated HSCs are the main source of collagen and other extracellular matrix (ECM) components, and emerging antifibrotic therapies are aimed at preventing ECM synthesis and deposition. MicroRNAs (miRNAs) hav...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Danping, Hu, Yibing, Xu, Wangwang, Yu, Huanhuan, Yang, Naibin, Ni, Shunlan, Fu, Rongquan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561992/ https://www.ncbi.nlm.nih.gov/pubmed/28586069 http://dx.doi.org/10.3892/mmr.2017.6702

Ejemplares similares

Tetramethylpyrazine inhibits CTGF and Smad2/3 expression and proliferation of hepatic stellate cells
por: Li, Jun, et al.
Publicado: (2015)

Deregulation of Regulatory T Cells in Acute-on-Chronic Liver Failure: A Rat Model
por: Ni, Shunlan, et al.
Publicado: (2017)

Long noncoding RNA LINC00958 accelerates the proliferation and matrix degradation of the nucleus pulposus by regulating miR-203/SMAD3
por: Zhao, Kunchi, et al.
Publicado: (2019)

miR-203-3p participates in the suppression of diabetes-associated osteogenesis in the jaw bone through targeting Smad1
por: Tang, Yuying, et al.
Publicado: (2018)

miR-96 promotes collagen deposition in keloids by targeting Smad7
por: Chao, Li, et al.
Publicado: (2019)

LncRNA CCAT2, involving miR-34a/TGF-β1/Smad4 signaling, regulate hepatic stellate cells proliferation
por: Gao, Haibing, et al.
Publicado: (2022)

MiR-34a and miR-203 Inhibit Survivin Expression to Control Cell Proliferation and Survival in Human Osteosarcoma Cells
por: Chen, Xun, et al.
Publicado: (2016)

miR-203 inhibits cell proliferation and ERK pathway in prostate cancer by targeting IRS-1
por: Meng, Yang, et al.
Publicado: (2020)

Inhibitory effects of oxymatrine on hepatic stellate cells activation through TGF-β/miR-195/Smad signaling pathway
por: Song, Li-Ying, et al.
Publicado: (2019)

miR-203 Regulates Cell Proliferation through Its Influence on Hakai Expression
por: Abella, Vanessa, et al.
Publicado: (2012)

Effect of TGF-β/smad signaling pathway blocking on expression profiles of miR-335, miR-150, miR-194, miR-27a, and miR-199a of hepatic stellate cells (HSCs)
por: Davoodian, Parivash, et al.
Publicado: (2017)

miR-203 Inhibits Alcohol-Induced Hepatic Steatosis by Targeting Lipin1
por: Cheng, Xiao-Yu, et al.
Publicado: (2018)

Glycyrrhetinic Acid-Induced MiR-663a Alleviates Hepatic Stellate Cell Activation by Attenuating the TGF-β/Smad Signaling Pathway
por: Guo, Xin-Xin, et al.
Publicado: (2020)

miR-654-5p Contributes to the Activation and Proliferation of Hepatic Stellate Cells by Targeting RXRα
por: Ma, Heming, et al.
Publicado: (2022)

Dihydroartemisinin inhibits the activation and proliferation of hepatic stellate cells by regulating miR-29b-3p
por: Huan, Sheng, et al.
Publicado: (2023)

miR‐193a/b‐3p relieves hepatic fibrosis and restrains proliferation and activation of hepatic stellate cells
por: Ju, Baoling, et al.
Publicado: (2019)

miR-203a-3p.1 is involved in the regulation of osteogenic differentiation by directly targeting Smad9 in MM-MSCs
por: Fan, Fang-Yi, et al.
Publicado: (2019)

HCP5 is a SMAD3-responsive long non-coding RNA that promotes lung adenocarcinoma metastasis via miR-203/SNAI axis
por: Jiang, Lin, et al.
Publicado: (2019)

The transient expression of miR-203 and its inhibiting effects on skeletal muscle cell proliferation and differentiation
por: Luo, W, et al.
Publicado: (2014)

miR-203 Suppresses the Proliferation and Migration and Promotes the Apoptosis of Lung Cancer Cells by Targeting SRC
por: Wang, Nan, et al.
Publicado: (2014)

miR-203 Inhibits Cell Proliferation and Migration of Lung Cancer Cells by Targeting PKCα
por: Wang, Chen, et al.
Publicado: (2013)

miR-203 inhibition of renal cancer cell proliferation, migration and invasion by targeting of FGF2
por: Xu, Mingxi, et al.
Publicado: (2015)

Downregulation of MiR-203a Disinhibits Bmi1 and Promotes Growth and Proliferation of Keratinocytes in Cholesteatoma
por: Zang, Jian, et al.
Publicado: (2018)

Circular RNA circSVIL Promotes Myoblast Proliferation and Differentiation by Sponging miR-203 in Chicken
por: Ouyang, Hongjia, et al.
Publicado: (2018)

MiR-203 Interplays with Polycomb Repressive Complexes to Regulate the Proliferation of Neural Stem/Progenitor Cells
por: Liu, Pei-Pei, et al.
Publicado: (2017)

miR‐203 inhibits augmented proliferation and metastasis of hepatocellular carcinoma residual in the promoted regenerating liver
por: Zheng, Xiao‐Bo, et al.
Publicado: (2017)

Epigenetic inactivation of the hsa-miR-203 in haematological malignancies
por: Chim, Chor Sang, et al.
Publicado: (2011)

miR-203 drives breast cancer cell differentiation
por: Martínez-Illescas, Nuria G., et al.
Publicado: (2023)

Loureirin B inhibits the proliferation of hepatic stellate cells and the Wnt/β-catenin signaling pathway by regulating miR-148-3p
por: Hu, Jian-Peng, et al.
Publicado: (2018)

Regulation of Cell Proliferation and Migration by miR-203 via GAS41/miR-10b Axis in Human Glioblastoma Cells
por: Pal, Dhananjaya, et al.
Publicado: (2016)

The miR-23b/27b/24-1 Cluster Inhibits Hepatic Fibrosis by Inactivating Hepatic Stellate Cells
por: Wan, Lin-Yan, et al.
Publicado: (2022)

Hepatocyte-derived exosomal miR-146a-5p inhibits hepatic stellate cell EMT process: a crosstalk between hepatocytes and hepatic stellate cells
por: Lang, Zhichao, et al.
Publicado: (2023)

miR-203 inhibits proliferation and self-renewal of leukemia stem cells by targeting survivin and Bmi-1
por: Zhang, Yi, et al.
Publicado: (2016)

Galectin-7 regulates keratinocyte proliferation and differentiation through JNK-miR-203-p63 signaling
por: Chen, Hung-Lin, et al.
Publicado: (2016)

The miR-203a Regulatory Network Affects the Proliferation of Chronic Myeloid Leukemia K562 Cells
por: He, Jinhua, et al.
Publicado: (2021)

HOTAIR/miR-203/CAV1 Crosstalk Influences Proliferation, Migration, and Invasion in the Breast Cancer Cell
por: Shi, Fuxiu, et al.
Publicado: (2022)

miR-203 and miR-221 regulate SOCS1 and SOCS3 in essential thrombocythemia
por: Navarro, A, et al.
Publicado: (2016)

Regulatory Role of miR-203 in Occurrence and Progression of Kazakh Esophageal squamous cell carcinoma
por: Hu, Jian Ming, et al.
Publicado: (2016)

The Roles of miR-26, miR-29, and miR-203 in the Silencing of the Epigenetic Machinery during Melanocyte Transformation
por: Gasque Schoof, Cláudia Regina, et al.
Publicado: (2015)

Plasma miR-155, miR-203, and miR-205 are Biomarkers for Monitoring of Primary Cutaneous T-Cell Lymphomas
por: Dusílková, Nina, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_4prqhbsj9v6bmenu1tudahijav