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Adiposity Amplifies the Genetic Risk of Fatty Liver Disease Conferred by Multiple Loci

Complex traits arise from the interplay between genetic and environmental factors. The actions of these factors usually appear to be additive, and few compelling examples of gene-environment synergy have been documented. Here we show that adiposity significantly amplifies the effect of three sequenc...

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Detalles Bibliográficos
Autores principales: Stender, Stefan, Kozlitina, Julia, Nordestgaard, Børge G., Tybjærg-Hansen, Anne, Hobbs, Helen H., Cohen, Jonathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562020/
https://www.ncbi.nlm.nih.gov/pubmed/28436986
http://dx.doi.org/10.1038/ng.3855