Regulation of type II collagen, matrix metalloproteinase-13 and cell proliferation by interleukin-1β is mediated by curcumin via inhibition of NF-κB signaling in rat chondrocytes

Curcumin possesses strong anti-inflammatory, anti-rheumatoid and anti-oxidative activities, and has the potential to inhibit nuclear factor-κB (NF-κB) signaling. Cartilage damage in osteoarthritis (OA) is largely mediated by interleukin-1β (IL-1β) via activation of various transcription factors, inc...

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Detalles Bibliográficos
Autores principales: Wang, Jian, Ma, Jie, Gu, Jian-Hua, Wang, Fu-Yong, Shang, Xiu-Shuai, Tao, Hai-Rong, Wang, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562050/
https://www.ncbi.nlm.nih.gov/pubmed/28627596
http://dx.doi.org/10.3892/mmr.2017.6771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562050/
https://www.ncbi.nlm.nih.gov/pubmed/28627596
http://dx.doi.org/10.3892/mmr.2017.6771

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